A liver profile is often ordered as part of routine health check-ups, to assess liver function, or to diagnose and monitor liver diseases. Interpretation of the results should be done by a healthcare professional who considers the entire clinical context and any additional tests that may be necessary. Abnormal results may prompt further investigations to determine the underlying cause of liver dysfunction. Here are some common components of a liver profile:

Liver Panel/Hepatic Function Panel: The liver panel is a group of blood tests that evaluate the overall health and function of the liver.

Total Protein: Total protein measurement assesses the total amount of protein in the blood, including albumin and globulin. Abnormal levels may indicate liver disease, kidney disease, or nutritional deficiencies.

Albumin: Albumin is a protein synthesized by the liver and plays a crucial role in maintaining blood volume and transporting various substances, such as hormones and drugs. Low levels of albumin may indicate liver disease or malnutrition.

Bilirubin (Total and Direct): Bilirubin is a waste product produced by the breakdown of red blood cells. Total bilirubin measures both unconjugated (indirect) and conjugated (direct) forms of bilirubin in the blood. Elevated levels may indicate liver dysfunction, bile duct obstruction, or hemolytic disorders.

Alkaline Phosphatase (Alk Phos): Alkaline phosphatase is an enzyme found in various tissues, including the liver, bones, and bile ducts. Elevated levels of alkaline phosphatase may indicate liver or bone disorders, such as liver disease or bone metastasis.

Alanine Aminotransferase (ALT):ALT is an enzyme primarily found in liver cells. It is released into the bloodstream when liver cells are damaged or inflamed. Elevated ALT levels are often indicative of liver injury or disease, such as hepatitis or fatty liver disease.

Aspartate Aminotransferase (AST): AST is another enzyme found in liver cells, as well as in the heart, muscles, and other tissues. Like ALT, elevated AST levels in the blood may indicate liver damage or injury. However, AST is less specific to the liver compared to ALT and can also be elevated in heart and muscle disorders.